SYCE1 and HSPB7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SYCE1	HSPB7
Description		synaptonemal complex central element protein 1	heat shock protein family B (small) member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element Nucleoplasm Chromosome Cytosol Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Cajal Body Actin Cytoskeleton Aggresome
	Molecular Function	Protein Binding	Protein Binding Protein C-terminus Binding Filamin Binding
	Biological Process	Synaptonemal Complex Assembly Cell Division	Response To Unfolded Protein Heart Development Regulation Of Heart Contraction
Pathways		Meiotic synapsis
Drugs
Diseases
GWAS			Arterial stiffness index ( 31235810) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction ( 30583798) Hypertrophic cardiomyopathy ( 33495596 33495597) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Systolic blood pressure ( 28739976)
Interacting Genes		49 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 CYTH3 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HOOK1 HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 LMNA MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM1 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124	20 interacting genes: APP BAG3 C22orf15 CEP76 DDIT4L DYNLT1 FLNA GUCD1 HSPB8 PDLIM7 PIP4K2B PLEKHF2 PRDM14 REL RERE SF3B4 SYCE1 TCF4 TEPSIN TRIM23
Entrez ID		93426	27129
HPRD ID		12598	13684
Ensembl ID		ENSG00000171772	ENSG00000173641
Uniprot IDs		A0A0B4J1R9 Q8N0S2	Q9UBY9
PDB IDs
Enriched GO Terms of Interacting Partners?
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