PRDM6 and KCTD9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRDM6	KCTD9
Description		PR/SET domain 6	potassium channel tetramerization domain containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	Protein Binding Histone Methyltransferase Activity Identical Protein Binding Metal Ion Binding	Protein Binding Identical Protein Binding Protein Self-association Cullin Family Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Histone Methylation Neurogenesis Negative Regulation Of Smooth Muscle Cell Differentiation	Protein Ubiquitination Intracellular Signal Transduction Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878 27618447) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Male-pattern baldness ( 28196072) Mammographic density (dense area) ( 25342443) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Percent mammographic density ( 25342443) Pulse pressure ( 27841878 27618447) QRS duration ( 25035420) Systolic blood pressure ( 26390057 27841878 27618447 30578418)	Lymphocyte counts ( 32888494)
Interacting Genes		70 interacting genes: ABI2 AGXT AHCYL1 ANKS1A AQP1 ARID5A ATPAF2 ATXN7L2 BAG3 BANF2 BANP C1orf109 CBFA2T2 CBX8 CCDC120 CCDC57 CCHCR1 CCNL1 CEP57L1 COX5B CSTF2 ELOA ENKD1 EXOSC5 FAM214B FAM90A1 FHL2 FOXD4L1 FRS3 FTO GADD45GIP1 GEM GPANK1 GRXCR1 HOXC8 IL16 IQUB KANK2 KAT5 KCTD9 KIFC3 LMO1 LMO2 LONRF1 MYOZ3 NCK2 NEK6 NFKBID PATZ1 PIH1D2 PRKAA2 PTK6 QARS1 RAD51D ROPN1 RUNX1T1 SAMD4A STK16 TCAF1 TEKT4 TLE5 TRIM14 TRMT12 TSGA10 TSGA10IP TSSK3 TTC23 UBASH3A USP54 ZFYVE26	94 interacting genes: ADAMTSL4 ANKS1A AQP1 ARID5A BANP BLZF1 C19orf54 C7orf31 C9orf24 CARD9 CBX8 CCDC33 CDC37 CDPF1 CFP CRADD CUL3 DDIT4L DEUP1 EHHADH EPM2AIP1 FAM124B GEM GOLGA6A GOLGA6L9 GORASP2 GPANK1 HOXA1 HOXC8 IGFN1 IL16 INCA1 KIF9 KLHL26 KRT31 KRT34 KRT35 KRT40 KRTAP13-2 KRTAP13-3 LNX1 LONRF1 MAD2L2 MBD3L1 MEOX2 MIIP MVP NDUFAB1 NIF3L1 NTAQ1 NUP35 PDZD4 PFDN5 PICK1 PLOD3 PNKD POF1B PPP1R16B PPP1R18 PPP1R32 PRDM6 PRKAA2 PSMA1 PSMB2 RBPMS RFX6 RUSC1 SDCBP SKP1 SLAIN1 SMARCB1 SMUG1 SPATS1 SPG21 STX11 SYT6 TASOR2 TEPSIN TEX37 TNS2 TRIM27 TRIM32 TRIM42 TRIP6 UNKL USP21 USP54 WDR83 ZBTB25 ZBTB42 ZNF408 ZNF426 ZNF620 ZNF76
Entrez ID		93166	54793
HPRD ID		19698	13772
Ensembl ID		ENSG00000061455	ENSG00000104756
Uniprot IDs		Q9NQX0	Q7L273
PDB IDs			5BXH
Enriched GO Terms of Interacting Partners?
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