SOCS6 and ZMIZ2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SOCS6	ZMIZ2
Description		suppressor of cytokine signaling 6	zinc finger MIZ-type containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Cytoplasm Cytosol Phosphatidylinositol 3-kinase Complex	Nucleus Nucleoplasm Mitochondrion Nuclear Replication Fork
	Molecular Function	Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Protein Binding Zinc Ion Binding Nuclear Receptor Coactivator Activity
	Biological Process	Defense Response Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Signal Transduction Proteasomal Protein Catabolic Process Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphate Biosynthetic Process Negative Regulation Of T Cell Activation	Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Chromatin-mediated Maintenance Of Transcription SMAD Protein Signal Transduction
Pathways		Regulation of KIT signaling Neddylation Negative regulation of FLT3
Drugs
Diseases
GWAS		Diverticular disease ( 30177863) Night sleep phenotypes ( 27126917) Systemic lupus erythematosus ( 18204098) Type 2 diabetes ( 29621232)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Fasting glucose ( 34059833) General cognitive ability ( 29844566) Hematocrit ( 32888494) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252)
Interacting Genes		40 interacting genes: ACVR1 AMOT APPL1 AR BMPR1B C1orf109 CLNK CRK DAB1 EFEMP1 EGFR ELOB ELOC ERBB2 ERBB3 ERBB4 FRS3 GAB1 INSR IRS2 IRS4 KDM1A KIT LNX1 MET PIK3R1 PIK3R2 PIK3R3 PITRM1 RBCK1 RELA SMURF2 TGFBR1 TUBA1A TUBB4B TXK UBE2D2 UBE2I WDR89 ZMIZ2	25 interacting genes: AR ARSJ ASB13 BANP C2orf88 CPNE7 CRCP FRS3 GCM2 INTS4 LRRC37A11P MCPH1 MVP NBL1 PIAS3 PIN1 RANBP3 SALL2 SCAMP1 SELENOV SOCS6 SS18L1 SSX2 TP53 TRAPPC6A
Entrez ID		9306	83637
HPRD ID		05491	13225
Ensembl ID		ENSG00000170677	ENSG00000122515
Uniprot IDs		A0A024R379 O14544	E7EWM3 Q8NF64
PDB IDs		2VIF
Enriched GO Terms of Interacting Partners?
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