OSMR and JAK1

  • Number of citations of the paper that reports this interaction (PubMedID 10586060)
  • 15
  • Data Source:
  • HPRD (in vivo)

OSMR

JAK1

Description oncostatin M receptor Janus kinase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 29875488)
  • Central retinal vein equivalent ( 31597446)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 26192919 28067908)
  • Daytime sleep phenotypes ( 27126917)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Hemoglobin levels ( 32327693)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Immature fraction of reticulocytes ( 32888494)
  • Inflammatory bowel disease ( 26192919 28067908)
  • Microalbuminuria ( 26631737)
  • Night sleep phenotypes ( 27126917)
  • Obesity-related traits ( 23251661)
  • Postoperative survival time in hepatocellular carcinoma ( 30945673 30945699)
  • Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)
  • Reticulocyte fraction of red cells ( 32888494)
  • Ulcerative colitis ( 26192919 28067908)
Interacting Genes 12 interacting genes: GAPDH GPRC5D IL6ST JAK1 JAK2 LHX2 MTDH OSM RGS4 SGTB SLC10A6 UBQLN2 81 interacting genes: ABL1 AGTR1 ANKRD13C BRCA1 BTK CBR1 CCR1 CCR5 CSF2RB CSF3R CXCR4 DAB1 DHX9 EIF2AK2 ELP2 ERBB2 FER FES GAB1 GHR GRB2 H3-4 IFNAR2 IFNGR1 IGF1R IL10RA IL21R IL2RB IL2RG IL3RA IL4R IL5RA IL6ST IL7R IL9R INPP5D INSR IRS1 IRS2 JAK2 JAK3 JAKMIP1 MDK NFYC OSMR P2RY1 P3H1 PDGFRA PDGFRB PIK3R1 PLA2G4A PLAUR PLCG2 PRKCZ PRMT5 PTK2B PTPN11 PTPN2 PTPN6 PTPRC RACK1 RAF1 SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT1 STAT2 STAT3 STAT5A STAT6 SYK TEC TNFRSF1A TOP1 TSHR TYK2 USP6 VNN2
Entrez ID 9180 3716
HPRD ID 03446 00992
Ensembl ID ENSG00000145623 ENSG00000162434
Uniprot IDs Q99650 P23458 Q6P669
PDB IDs 3EYG 3EYH 4E4L 4E4N 4E5W 4EHZ 4EI4 4FK6 4GS0 4I5C 4IVB 4IVC 4IVD 4K6Z 4K77 4L00 4L01 5E1E 5HX8 5IXD 5IXI 5KHW 5KHX 5L04 5WO4 6AAH 6BBU 6C7Y 6DBN 6ELR 6GGH 6HZU 6N77 6N78 6N79 6N7A 6N7B 6N7C 6N7D 6RSB 6RSC 6RSD 6RSE 6RSH 6SM8 6SMB 6TPE 6TPF 6W8L
Enriched GO Terms of Interacting Partners?
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