PDCD5 and ACP5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PDCD5	ACP5
Description		programmed cell death 5	acid phosphatase 5, tartrate resistant
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Lysosome Cytosol Integral Component Of Membrane
	Molecular Function	DNA Binding Protein Binding Heparin Binding Acetyltransferase Activator Activity Beta-tubulin Binding	Acid Phosphatase Activity Ferrous Iron Binding Ferric Iron Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Insertion Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding	Dephosphorylation Response To Lipopolysaccharide Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-12 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Superoxide Anion Generation Response To Cytokine Negative Regulation Of Nitric Oxide Biosynthetic Process Bone Resorption Negative Regulation Of Inflammatory Response Defense Response To Gram-positive Bacterium Bone Morphogenesis
Pathways			Vitamin B2 (riboflavin) metabolism
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Glycated hemoglobin levels ( 34059833) Immature fraction of reticulocytes ( 32888494) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Platelet count ( 32888494) Red cell distribution width ( 32888494 27863252) Systemic lupus erythematosus ( 33272962)	Blood protein levels ( 30072576 29875488) Multiple sclerosis (severity) ( 19010793)
Interacting Genes		16 interacting genes: ACP5 CDC42 CEP126 EEF1G GGCX KAT5 KDM1A LRIF1 NUDT3 OTUD5 PICK1 RAD18 TRIM35 UBE2D3 UTP14A VHL	11 interacting genes: EGR2 GPC4 MAPK9 PDCD5 PPP2CB RPA2 SLC35F6 SNRNP40 SPP1 TNFSF10 ZBTB16
Entrez ID		9141	54
HPRD ID		06843	01374
Ensembl ID		ENSG00000105185	ENSG00000102575
Uniprot IDs		O14737	A0A024R7F8 P13686
PDB IDs		1YYB 2CRU 2K6B	1WAR 2BQ8
Enriched GO Terms of Interacting Partners?
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