ACP5 and PDCD5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACP5	PDCD5
Description		acid phosphatase 5, tartrate resistant	programmed cell death 5
Image
GO Annotations	Cellular Component	Lysosome Cytosol Integral Component Of Membrane	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Acid Phosphatase Activity Ferrous Iron Binding Ferric Iron Binding	DNA Binding Protein Binding Heparin Binding Acetyltransferase Activator Activity Beta-tubulin Binding
	Biological Process	Dephosphorylation Response To Lipopolysaccharide Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-12 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Superoxide Anion Generation Response To Cytokine Negative Regulation Of Nitric Oxide Biosynthetic Process Bone Resorption Negative Regulation Of Inflammatory Response Defense Response To Gram-positive Bacterium Bone Morphogenesis	Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Insertion Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding
Pathways		Vitamin B2 (riboflavin) metabolism
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Multiple sclerosis (severity) ( 19010793)	Blood protein levels ( 29875488) Glycated hemoglobin levels ( 34059833) Immature fraction of reticulocytes ( 32888494) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Platelet count ( 32888494) Red cell distribution width ( 32888494 27863252) Systemic lupus erythematosus ( 33272962)
Interacting Genes		11 interacting genes: EGR2 GPC4 MAPK9 PDCD5 PPP2CB RPA2 SLC35F6 SNRNP40 SPP1 TNFSF10 ZBTB16	16 interacting genes: ACP5 CDC42 CEP126 EEF1G GGCX KAT5 KDM1A LRIF1 NUDT3 OTUD5 PICK1 RAD18 TRIM35 UBE2D3 UTP14A VHL
Entrez ID		54	9141
HPRD ID		01374	06843
Ensembl ID		ENSG00000102575	ENSG00000105185
Uniprot IDs		A0A024R7F8 P13686	O14737
PDB IDs		1WAR 2BQ8	1YYB 2CRU 2K6B
Enriched GO Terms of Interacting Partners?
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