ATG12 and SRP19

		ATG12	SRP19
Description		autophagy related 12	signal recognition particle 19
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GO Annotations	Cellular Component	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex	Nucleolus Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle
	Molecular Function	Protein Binding	RNA Binding Protein Binding 7S RNA Binding Ribosome Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Autophagy Of Nucleus	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition
Pathways		Macroautophagy Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling	SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		16 interacting genes: APP ATG10 ATG3 ATG5 ATG7 CRX DOCK9 IER2 KRTAP4-12 MDFI MEOX2 PLSCR1 PTK2 SERTAD1 SERTAD2 SRP19	10 interacting genes: AP3S1 APP ATG12 IPO5 IPO7 IPO8 KPNA1 MAPK8IP2 SRP54 TNPO1
Entrez ID		9140	6728
HPRD ID		08496	01644
Ensembl ID		ENSG00000145782	ENSG00000153037
Uniprot IDs		O94817	A0A087WYR0 A0A2U3TZN1 P09132
PDB IDs		4GDK 4GDL 4NAW	1JID 1MFQ 1RY1 2J37 3KTV 4P3E 5M73
Enriched GO Terms of Interacting Partners?
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