ATG12 and SERTAD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATG12	SERTAD1
Description		autophagy related 12	SERTA domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Transcription Regulator Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Autophagy Of Nucleus	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription By RNA Polymerase II Chromatin-mediated Maintenance Of Transcription
Pathways		Macroautophagy Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301)	Monocyte percentage of white cells ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		16 interacting genes: APP ATG10 ATG3 ATG5 ATG7 CRX DOCK9 IER2 KRTAP4-12 MDFI MEOX2 PLSCR1 PTK2 SERTAD1 SERTAD2 SRP19	57 interacting genes: ADCY1 ASB8 ATG12 ATXN7L3 BANF2 C1orf109 CCND2 CDK4 CDKN2A CHAF1A CHURC1 CIB3 CINP CKS1B COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAAP20 FAH FNDC11 FXR1 GLYCTK HIVEP1 HSPB1 KAT2B KLC4 KLHL42 MVP NEDD4 P4HA3 PATE1 PBX4 PICK1 PIH1D2 POT1 PRDM4 PSORS1C2 RBX1 RCHY1 ROPN1 SEC14L4 SETD7 SFI1 SMAD3 SPEN SSX7 STAT5B SUPT7L TGM2 TLR4 TRIM28 TSC1 XIAP ZNF410
Entrez ID		9140	29950
HPRD ID		08496	15326
Ensembl ID		ENSG00000145782	ENSG00000197019
Uniprot IDs		O94817	Q53GC0 Q9UHV2
PDB IDs		4GDK 4GDL 4NAW
Enriched GO Terms of Interacting Partners?
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