ACVR1B and SHMT2

ACVR1B

SHMT2

Description activin A receptor type 1B serine hydroxymethyltransferase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 25 interacting genes: ACVR2B BAG6 BAMBI BMPR2 FKBP1A IGSF1 INHBA INHBB INHBC NEDD4L NODAL OS9 OTUB1 PRKACB RXRA SHMT2 SMAD2 SMAD4 SMAD7 SNX1 SNX2 TDGF1 TGFBRAP1 TUBA1A TUBA1C 28 interacting genes: ABRAXAS2 ACVR1B APP ARL6IP1 BABAM1 BABAM2 BRCC3 CAB39 CFTR CLEC2D CMTM5 COMMD6 CREB3 CSNK2B DUX4 ESR1 FBXO7 KASH5 KMT2D MAL2 NDRG1 NKD2 OGT PPARD PRKAG1 RND1 SCAF11 TUBA1C
Entrez ID 91 6472
HPRD ID 03193 00717
Ensembl ID ENSG00000135503 ENSG00000182199
Uniprot IDs P36896 A0A024RB99 B4DJQ3 B4DLV4 P34897 Q5BJF5 Q5HYG8 V9HW06
PDB IDs 4PVF 5V7I 5X3V 6DK3 6H3C 6M5O 6QVG 6QVL 6R8F
Enriched GO Terms of Interacting Partners?
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