ZNF622 and MELK

Number of citations of the paper that reports this interaction (PubMedID 11802789)
24

Data Source:
HPRD (in vivo, two hybrid)

		ZNF622	MELK
Description		zinc finger protein 622	maternal embryonic leucine zipper kinase
Image
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Golgi Apparatus Cytosol Preribosome, Large Subunit Precursor	Plasma Membrane Cell Cortex Membrane
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Calcium Ion Binding Protein Binding ATP Binding Lipid Binding Protein Serine Kinase Activity
	Biological Process	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Kinase Activity Ribosomal Large Subunit Biogenesis Positive Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade	G2/M Transition Of Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Cell Population Proliferation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Peptidyl-tyrosine Phosphorylation Hemopoiesis Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Protein Autophosphorylation Neural Precursor Cell Proliferation
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Attention function in attention deficit hyperactive disorder ( 26174813)
Interacting Genes		9 interacting genes: APP BEND7 CDC42 HMGB2 MACROH2A1 MELK MYBL2 OGT PRKN	11 interacting genes: CDC25B CDC5L EIF2S1 EZH2 H1-5 LMNB1 MAPT MBP PPP1R8 SF3B1 ZNF622
Entrez ID		90441	9833
HPRD ID		12278	06119
Ensembl ID		ENSG00000173545	ENSG00000165304
Uniprot IDs		Q969S3	B7Z1G6 Q14680
PDB IDs		6LQM 6LSR	4BKY 4BKZ 4BL1 4D2P 4D2T 4D2V 4D2W 4IXP 4UMP 4UMQ 4UMR 4UMT 4UMU 5IH8 5IH9 5IHA 5IHC 5K00 5M5A 5MAF 5MAG 5MAH 5MAI 5TVT 5TWL 5TWU 5TWY 5TWZ 5TX3 6GVX 6VXR
Enriched GO Terms of Interacting Partners?
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