MELK

Description		maternal embryonic leucine zipper kinase
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GO Annotations	Cellular Component	Plasma Membrane Cell Cortex Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Calcium Ion Binding Protein Binding ATP Binding Lipid Binding Protein Serine Kinase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Cell Population Proliferation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Peptidyl-tyrosine Phosphorylation Hemopoiesis Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Protein Autophosphorylation Neural Precursor Cell Proliferation
Pathways
Drugs		Fostamatinib
Diseases
GWAS
Interacting Genes		11 interacting genes: CDC25B CDC5L EIF2S1 EZH2 H1-5 LMNB1 MAPT MBP PPP1R8 SF3B1 ZNF622
Entrez ID		9833
HPRD ID		06119
Ensembl ID		ENSG00000165304
Uniprot IDs		B7Z1G6 Q14680
PDB IDs		4BKY 4BKZ 4BL1 4D2P 4D2T 4D2V 4D2W 4IXP 4UMP 4UMQ 4UMR 4UMT 4UMU 5IH8 5IH9 5IHA 5IHC 5K00 5M5A 5MAF 5MAG 5MAH 5MAI 5TVT 5TWL 5TWU 5TWY 5TWZ 5TX3 6GVX 6VXR
Enriched GO Terms of Interacting Partners?
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