PLOD3 and CRIP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLOD3	CRIP3
Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	cysteine rich protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome	Cytoplasm
	Molecular Function	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity	Metal Ion Binding
	Biological Process	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Lung Morphogenesis Basement Membrane Assembly
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Ascorbic acid
Diseases
GWAS		Blood protein levels ( 30072576)	Adult hearing difficulty ( 31564434) Autism spectrum disorder or schizophrenia ( 28540026) Diastolic blood pressure ( 30487518) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Estimated glomerular filtration rate ( 31152163) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Hypertension ( 30487518) Mean arterial pressure ( 30487518) Pulse pressure ( 27841878 30487518) Systolic blood pressure ( 27841878 30487518) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		20 interacting genes: CCDC85B COIL COL17A1 CRIP3 DPPA2 EFHC2 EHMT2 FAM153A IP6K2 KCTD9 KHNYN L3MBTL3 LINC00839 NAB2 RAB3IP RALY RHOU RHOXF2 SORBS3 ZNF620	2 interacting genes: FHL3 PLOD3
Entrez ID		8985	401262
HPRD ID		04347	16755
Ensembl ID		ENSG00000106397	ENSG00000146215
Uniprot IDs		O60568 Q9UG85	Q6Q6R5
PDB IDs		6FXK 6FXM 6FXR 6FXT 6FXX 6FXY
Enriched GO Terms of Interacting Partners?
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