CRIP3 and PLOD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CRIP3	PLOD3
Description		cysteine rich protein 3	procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Metal Ion Binding	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity
	Biological Process		In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Lung Morphogenesis Basement Membrane Assembly
Pathways			Collagen biosynthesis and modifying enzymes
Drugs			Ascorbic acid
Diseases
GWAS		Adult hearing difficulty ( 31564434) Autism spectrum disorder or schizophrenia ( 28540026) Diastolic blood pressure ( 30487518) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Estimated glomerular filtration rate ( 31152163) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Hypertension ( 30487518) Mean arterial pressure ( 30487518) Pulse pressure ( 27841878 30487518) Systolic blood pressure ( 27841878 30487518) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood protein levels ( 30072576)
Interacting Genes		2 interacting genes: FHL3 PLOD3	20 interacting genes: CCDC85B COIL COL17A1 CRIP3 DPPA2 EFHC2 EHMT2 FAM153A IP6K2 KCTD9 KHNYN L3MBTL3 LINC00839 NAB2 RAB3IP RALY RHOU RHOXF2 SORBS3 ZNF620
Entrez ID		401262	8985
HPRD ID		16755	04347
Ensembl ID		ENSG00000146215	ENSG00000106397
Uniprot IDs		Q6Q6R5	O60568 Q9UG85
PDB IDs			6FXK 6FXM 6FXR 6FXT 6FXX 6FXY
Enriched GO Terms of Interacting Partners?
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