TOP3B and UPF2

  • Number of citations of the paper that reports this interaction (PubMedID 15231747)
  • 57
  • Data Source:
  • BioGRID (two hybrid)

TOP3B

UPF2

Description DNA topoisomerase III beta UPF2 regulator of nonsense mediated mRNA decay
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Attention function in attention deficit hyperactive disorder ( 26174813)
  • Bipolar disorder ( 31043756)
  • Diastolic blood pressure ( 29208002)
  • Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Interacting Genes 24 interacting genes: ADAMTSL4 AXIN2 BHLHB9 C1QBP CENPF CHD8 CHIC2 CIAO1 FASTK FBLN5 GRN KANK2 KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF250 ZNF408 78 interacting genes: ABCF2 AGPAT1 AKTIP ART4 ATP1B3 BLM CALR CENPU CIZ1 COMTD1 CYBA DCP1B DCP2 DPF2 E4F1 EIF1 EIF4A1 EIF4G1 ENO1 EXOSC1 EXOSC10 EXOSC4 EXOSC6 EXOSC8 GADD45GIP1 GATA3 HBZ HMGA1 HS3ST3A1 HSF2BP ITGB1 KRT18 LDHA LSM1 MAP1A MAP1LC3B MIF MRPL40 MTERF3 MTREX MYB NDUFA7 NOB1 NOMO1 NOP53 PHB2 PITX1 PUF60 RNPS1 RPL13 RPL5 RPL8 RPS15 RPS25 RPS6 RPS7 RRP7A RSRC2 SERBP1 SERF2 SMG1 SSBP2 SUMO3 TK1 TNNI2 TOP3B TUBB2A TYMS UPF1 UPF3B WNK1 XRN1 XRN2 ZBTB48 ZFP36 ZGPAT ZNF408 ZNF44
Entrez ID 8940 26019
HPRD ID 04662 10405
Ensembl ID ENSG00000100038 ENSG00000151461
Uniprot IDs A0A024R1C2 A8K4N2 O95985 Q9HAU5
PDB IDs 5GVC 5GVE 1UW4 2WJV 4CEK 4CEM
Enriched GO Terms of Interacting Partners?
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