TNFRSF10C and DNAJC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TNFRSF10C	DNAJC1
Description		TNF receptor superfamily member 10c	DnaJ heat shock protein family (Hsp40) member C1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Anchored Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding	ATPase Activator Activity DNA Binding Protein Binding Chaperone Binding
	Biological Process	TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process	Regulation Of Translation Protein Folding Negative Regulation Of Proteolysis Regulation Of Protein Secretion Regulation Of Catalytic Activity
Pathways		TP53 Regulates Transcription of Death Receptors and Ligands
Drugs
Diseases
GWAS		Basophil count ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte count ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)	Aspartate aminotransferase levels ( 33339817) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683 23535729) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Essential hypertension (time to event) ( 32589924) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Oily fish consumption ( 32066663) Ovarian cancer ( 23535730) Pork consumption ( 32066663) Raw vegetable consumption ( 32066663) Subcutaneous adipose tissue ( 26480920) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		34 interacting genes: APOA1 AQP6 ARL13B ASZ1 CD79A COQ9 CREB3L1 CXCL14 CYB5R3 DNAJC1 ERGIC3 FAM209A GPR152 GPR37L1 KCNJ6 KCNK5 LMNA LRSAM1 MGST1 MRPS18B PDZK1IP1 RAP1A RFLNB SGTA SLC27A6 SLC30A4 SRPK1 SRPK2 STOM SYAP1 TMEM45B TMEM80 TNFSF10 ZHX1	11 interacting genes: ABHD16A AGTRAP ATP6V0C CMTM7 CYP4F2 HSPA5 ITIH4 PLP2 SERPINA3 TMEM201 TNFRSF10C
Entrez ID		8794	64215
HPRD ID		04681	09922
Ensembl ID		ENSG00000173535	ENSG00000136770
Uniprot IDs		O14798	Q96KC8
PDB IDs			2CQQ 2CQR
Enriched GO Terms of Interacting Partners?
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