MPDZ and PLEKHA2

Number of citations of the paper that reports this interaction (PubMedID 11802782)
37

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		MPDZ	PLEKHA2
Description		multiple PDZ domain crumbs cell polarity complex component	pleckstrin homology domain containing A2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Bicellular Tight Junction Postsynaptic Density Apical Plasma Membrane Apicolateral Plasma Membrane Dendrite Apical Part Of Cell	Nucleus Cytoplasm Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	Protein Binding Protein C-terminus Binding	Fibronectin Binding Protein Binding Lipid Binding PDZ Domain Binding Laminin Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Microtubule Organizing Center Organization Regulation Of Microtubule Cytoskeleton Organization Tight Junction Assembly	Positive Regulation Of Cell-matrix Adhesion
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159 29760442) Corneal hysteresis ( 32716492 30894546) Corneal structure ( 23291589) Heel bone mineral density ( 30598549 28869591) Refractive astigmatism ( 30306274) Triglyceride levels ( 32203549)	High density lipoprotein cholesterol levels ( 31211820) Monocyte percentage of white cells ( 32888494)
Interacting Genes		16 interacting genes: ABCA1 CAMK2A CLDN1 CLDN5 CRHR1 CSPG4 DRD3 F11R HTR2C KIT MTNR1A PLEKHA1 PLEKHA2 RNF5 SYNGAP1 TSC22D2	19 interacting genes: COG6 DLG2 DLG3 EGLN3 FHL5 GIPC1 GIPC2 GIPC3 GOLGA2 HSF2BP KANK2 LNX1 M1AP MPDZ PLEKHA1 PTPN13 SNTG1 TEPSIN TRIM23
Entrez ID		8777	59339
HPRD ID		09155
Ensembl ID		ENSG00000107186	ENSG00000169499
Uniprot IDs		O75970	A0A087WZ32 A8K727 Q9HB19
PDB IDs		2FCF 2FNE 2IWN 2IWO 2IWP 2IWQ 2O2T 2OPG 2QG1
Enriched GO Terms of Interacting Partners?
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