CBLB and VAV3

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

CBLB

VAV3

Description Cbl proto-oncogene B vav guanine nucleotide exchange factor 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
  • Asthma and hay fever ( 24388013)
  • Autoimmune thyroid disease ( 32581359)
  • Bipolar disorder ( 31043756)
  • Differentiated thyroid cancer ( 28703219)
  • Eosinophil percentage of white cells ( 32888494)
  • Facial wrinkles (principal components analysis) ( 33959940)
  • Hashimoto thyroiditis versus Graves' disease ( 25429627)
  • Hip circumference adjusted for BMI ( 28552196)
  • Hypothyroidism ( 30367059 27182965 22493691)
  • IgA nephropathy ( 25305756)
  • Medication use (thyroid preparations) ( 31015401)
  • Night sleep phenotypes ( 27126917)
  • Papillary thyroid cancer ( 28703219)
  • Plasma thyroid-stimulating hormone levels ( 24722205)
  • Refractive error ( 32231278)
  • Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Thyroid stimulating hormone levels ( 32769997)
  • Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes 55 interacting genes: APPL1 ARHGEF7 BLNK CD2AP CRK CRKL CRY1 DAPK1 DUXAP9 EGFR FLT3 FYB1 FYN GLRX3 GORASP2 GRAP2 GRB2 HNRNPK IFT57 KIT LRRK1 LRRK2 MFHAS1 NCK1 NCK2 NEDD4 NEDD8 OSTF1 PIK3R1 PLCG2 PRMT2 PTK6 RET RNF11 SH3KBP1 SH3RF1 SHC1 SORBS2 SORBS3 SP7 SPRY2 SYK TGFB1I1 TNFRSF11A UBASH3A UBASH3B UBC UBE2D2 UBE2L3 VAV1 VAV2 VAV3 VPS26C YES1 ZAP70 25 interacting genes: AR CBLB EGFR ERBB2 ERBB3 ERBB4 ESR1 GAB1 GRB2 IGF1R INSR KIT LCP2 MET PIK3R1 PLCG1 RAC1 RHOA RHOG RINT1 ROS1 SH3BP2 SHC1 ZRANB1 ZYX
Entrez ID 868 10451
HPRD ID 05136 05706
Ensembl ID ENSG00000114423 ENSG00000134215
Uniprot IDs B3KSS7 B4DYP3 B7ZAG1 Q13191 Q9UKW4
PDB IDs 2AK5 2BZ8 2DO6 2J6F 2JNH 2LDR 2OOA 2OOB 3PFV 3VGO 3ZNI 2D86
Enriched GO Terms of Interacting Partners?
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