VAV3 and SHC1

  • Number of citations of the paper that reports this interaction (PubMedID 11094073)
  • 48
  • Data Source:
  • HPRD (in vivo)

VAV3

SHC1

Description vav guanine nucleotide exchange factor 3 SHC adaptor protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
  • Asthma and hay fever ( 24388013)
  • Autoimmune thyroid disease ( 32581359)
  • Bipolar disorder ( 31043756)
  • Differentiated thyroid cancer ( 28703219)
  • Eosinophil percentage of white cells ( 32888494)
  • Facial wrinkles (principal components analysis) ( 33959940)
  • Hashimoto thyroiditis versus Graves' disease ( 25429627)
  • Hip circumference adjusted for BMI ( 28552196)
  • Hypothyroidism ( 30367059 27182965 22493691)
  • IgA nephropathy ( 25305756)
  • Medication use (thyroid preparations) ( 31015401)
  • Night sleep phenotypes ( 27126917)
  • Papillary thyroid cancer ( 28703219)
  • Plasma thyroid-stimulating hormone levels ( 24722205)
  • Refractive error ( 32231278)
  • Response to antiepileptic mood-stabilizing treatment in bipolar disorder ( 32627186)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
  • Thyroid stimulating hormone levels ( 32769997)
  • Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes 25 interacting genes: AR CBLB EGFR ERBB2 ERBB3 ERBB4 ESR1 GAB1 GRB2 IGF1R INSR KIT LCP2 MET PIK3R1 PLCG1 RAC1 RHOA RHOG RINT1 ROS1 SH3BP2 SHC1 ZRANB1 ZYX 146 interacting genes: ALK AP2A1 AP2A2 APP AR AXL BCL3 BCR BUB1 C11orf58 CALCOCO2 CALD1 CBL CBLB CBLC CD22 CD247 CD3E CD81 CDH5 CEACAM1 CRK CRKL CSF1R CSF2RB CSF3R CSK DAG1 DDR1 DDR2 DNAH7 DOK1 DUSP23 EGFR EPHA2 EPOR EPS8 ERBB2 ERBB3 ERBB4 ESR1 FAM118B FBXW7 FCGR2A FCGR3A FGFR1 FGFR2 FLT1 FLT3 FLT4 FYN GAB1 GAB2 GEMIN7 GH1 GHR GRAP GRAP2 GRB2 GRB7 HMOX2 IGF1R IL2 IL2RB IL2RG IL4R IL6ST ILK INPP5D INPPL1 INSR IRS1 IRS2 ITGB3 ITGB4 JAK2 KDR KIT KRT18 LCK LCP2 LRP1 LTK LYN MAP4K1 MAPK1 MAPK14 MAPK6 MAPK8 MAPKAPK2 MET MME MPL MRPL44 MST1R NGFR NPM1 NTRK1 NTRK2 NTRK3 NUDT21 OSGEP PAG1 PAK1 PDGFRB PIK3C2B PIK3R1 PIK3R2 PLCG1 PLCG2 PLPP3 PLSCR1 PPP2R5A PRKCA PRKCD PRKRA PTK2 PTK2B PTPN11 PTPN12 PTPN2 PTPN6 RAPGEF1 RASA1 RB1 RET SH2B2 SHCBP1 SMAD4 SOS1 SOS2 SP1 SRC STAT5A STAT5B SUV39H2 SYK TEC TEK TH TPR TRIM15 UBASH3B VAV1 VAV3 ZAP70
Entrez ID 10451 6464
HPRD ID 05706 02780
Ensembl ID ENSG00000134215 ENSG00000160691
Uniprot IDs Q9UKW4 P29353
PDB IDs 2D86 1MIL 1N3H 1OY2 1QG1 1SHC 1TCE 1WCP 2L1C 4JMH 4XWX 5CZI 6DM4
Enriched GO Terms of Interacting Partners?
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