BECN1 and ITPR3

  • Number of citations of the paper that reports this interaction (PubMedID 22082873)
  • 59
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

BECN1

ITPR3

Description beclin 1 inositol 1,4,5-trisphosphate receptor type 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Type 2 diabetes (age of onset) ( 28060188)
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Asthma and attention deficit hyperactivity disorder ( 31619474)
  • Body mass index ( 26426971)
  • Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
  • Crohn's disease ( 23850713)
  • Educational attainment ( 23722424)
  • Hodgkin's lymphoma ( 30194254)
  • Multiple sclerosis and body mass index (pleiotropy) ( 26920376)
  • Obesity (extreme) ( 19553259)
  • Phosphorus levels ( 20558539)
  • Regular attendance at a gym or sports club ( 29970889)
  • Total carotid plaque area (excess vs minimal atherosclerosis) ( 32811377)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes 57 interacting genes: AKT1 AMBRA1 ARAF ARNT BCL2 BCL2L1 BCL2L10 BTK CASP3 CCND2 CDK4 CDK6 CDKN2A CDKN2B EPHA2 ERBB2 FGFR4 FRS2 FZR1 GFI1B GLIS2 GOPC GRM1 HERC5 ITCH ITPR1 ITPR3 KAT2A KDELR2 LATS2 MAP2K3 MAP2K5 MAP2K6 MAPKAPK2 MAPKAPK3 MDM4 MST1 NF2 NXF1 PDGFRA PGK1 RACK1 RAF1 SENP3 SGF29 SHD SMAD2 STK11 STYK1 TEAD2 TERT TSC1 UBC ULK1 WASHC1 XPO1 YES1 18 interacting genes: AKT1 ANK1 BAP1 BECN1 CABP1 ITPR1 MTDH MTNR1A MTNR1B SIGMAR1 TRPC1 TRPC2 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPM2
Entrez ID 8678 3710
HPRD ID 05087 00926
Ensembl ID ENSG00000126581 ENSG00000096433
Uniprot IDs A0A024R1X5 B4DQ36 E7EV84 Q14457 W0FFG4 A6H8K3 Q14573 Q59ES2
PDB IDs 2P1L 2PON 3DVU 4DDP 4MI8 5EFM 5HHE 5VAU 5VAX 5VAY 6DCN 6DCO 6HOI 6HOJ 6HOK 7BL1 6DQJ 6DQN 6DQS 6DQV 6DQZ 6DR0 6DR2 6DRA 6DRC 6UQK
Enriched GO Terms of Interacting Partners?
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