ITPR3 and TRPC6

  • Number of citations of the paper that reports this interaction (PubMedID 11290752)
  • 84
  • Data Source:
  • HPRD (in vitro)

ITPR3

TRPC6

Description inositol 1,4,5-trisphosphate receptor type 3 transient receptor potential cation channel subfamily C member 6
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Asthma and attention deficit hyperactivity disorder ( 31619474)
  • Body mass index ( 26426971)
  • Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
  • Crohn's disease ( 23850713)
  • Educational attainment ( 23722424)
  • Hodgkin's lymphoma ( 30194254)
  • Multiple sclerosis and body mass index (pleiotropy) ( 26920376)
  • Obesity (extreme) ( 19553259)
  • Phosphorus levels ( 20558539)
  • Regular attendance at a gym or sports club ( 29970889)
  • Total carotid plaque area (excess vs minimal atherosclerosis) ( 32811377)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
  • Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429)
  • Daytime nap ( 33568662)
  • General risk tolerance (MTAG) ( 30643258)
  • Lung adenocarcinoma ( 28604730)
  • Menarche (age at onset) ( 25231870)
  • Monocyte count ( 32888494)
  • Plateletcrit ( 32888494)
  • Severity of nausea and vomiting of pregnancy ( 29563502)
  • White blood cell count ( 32888494)
Interacting Genes 18 interacting genes: AKT1 ANK1 BAP1 BECN1 CABP1 ITPR1 MTDH MTNR1A MTNR1B SIGMAR1 TRPC1 TRPC2 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPM2 9 interacting genes: FYN ITPR3 MX1 ORAI1 RNF24 SRC TRPC3 TRPC7 TRPM2
Entrez ID 3710 7225
HPRD ID 00926 04710
Ensembl ID ENSG00000096433 ENSG00000137672
Uniprot IDs A6H8K3 Q14573 Q59ES2 Q9Y210
PDB IDs 6DQJ 6DQN 6DQS 6DQV 6DQZ 6DR0 6DR2 6DRA 6DRC 6UQK 5YX9 6UZ8 6UZA 7A6U
Enriched GO Terms of Interacting Partners?
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