EIF3F and TIMM10B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, two hybrid)

		EIF3F	TIMM10B
Description		eukaryotic translation initiation factor 3 subunit F	translocase of inner mitochondrial membrane 10B
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GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Intermembrane Space Protein Transporter Complex TIM22 Mitochondrial Import Inner Membrane Insertion Complex
	Molecular Function	Translation Initiation Factor Activity Thiol-dependent Deubiquitinase Protein Binding Metallopeptidase Activity Translation Initiation Factor Binding Identical Protein Binding Isopeptidase Activity Deubiquitinase Activity	Protein Binding Metal Ion Binding Unfolded Protein Binding Protein Transporter Activity
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Protein Deubiquitination IRES-dependent Viral Translational Initiation	Cell-matrix Adhesion Protein Insertion Into Mitochondrial Inner Membrane
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	Mitochondrial protein import
Drugs		Quercetin
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depression (quantitative trait) ( 20800221) Malaria ( 31844061) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Malaria ( 31844061)
Interacting Genes		45 interacting genes: AGR2 APP ATXN1 C1orf216 C6orf201 CCDC120 CCDC196 CDC42 CDK11A CDK11B CDK19 CDSN COL1A2 DKC1 EEF1A1 EIF3M EML2 ERCC6 FBXO32 HAX1 HGS HNRNPK HTR2A MCPH1 MKRN2 MSH4 MTOR MYDGF MYOZ1 NUP54 OGT PBX4 PKN1 POGZ POU6F2 PTN RABIF RIN1 RPS6KB1 RTP5 SHBG SMAD9 SUOX TIMM10B WASHC1	8 interacting genes: EIF3F HGS KLHL38 LDHC MBD3 MEIS2 PLD2 RPLP2
Entrez ID		8665	26515
HPRD ID		04887	16242
Ensembl ID		ENSG00000175390	ENSG00000132286
Uniprot IDs		O00303	B2R4A9 Q9Y5J6
PDB IDs		3J8B 3J8C 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09	7CGP
Enriched GO Terms of Interacting Partners?
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