IRS2 and UBTF

  • Number of citations of the paper that reports this interaction (PubMedID 12554758)
  • 29
  • Data Source:
  • HPRD (in vivo)

IRS2

UBTF

Description insulin receptor substrate 2 upstream binding transcription factor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Diverticular disease ( 30177863)
  • hemolysis of donated blood (osmotic) ( 34014839)
  • Mean corpuscular hemoglobin concentration ( 29403010)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes 50 interacting genes: ATP2A1 ATP2A2 BCL2L1 CDKL1 CRK CUL4A EDEM1 EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 LAMP1 MPL MPO MTDH NEDD4 NRAS NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PROZ PTPN11 PTPN6 PTPRF PTPRR RAP2A RPTOR SHC1 SLC35B1 SOCS1 SOCS3 SOCS6 SOCS7 SRPK2 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ 34 interacting genes: AURKA CCNA2 CCND1 CCNE1 CDK2 CDK4 CENPC CHGB CREBBP CSNK2A1 EP300 GSK3A IRS1 IRS2 LEF1 MAD1L1 MAPK1 MAPK3 MDM2 POLR1E POLR1G RB1 RBL2 RUNX2 SERPINH1 SMURF1 TAF1 TAF1A TAF1B TAF1C TAF1D TBP TCOF1 ZMYM2
Entrez ID 8660 7343
HPRD ID 02878 02814
Ensembl ID ENSG00000185950 ENSG00000108312
Uniprot IDs Q9P084 Q9Y4H2 P17480
PDB IDs 3FQW 3FQX 1K99 1L8Y 1L8Z 2HDZ
Enriched GO Terms of Interacting Partners?
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