IRS2 and PIK3R2

  • Number of citations of the paper that reports this interaction (PubMedID 9651378)
  • 53
  • Data Source:
  • HPRD (in vivo, in vitro)

IRS2

PIK3R2

Description insulin receptor substrate 2 phosphoinositide-3-kinase regulatory subunit 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Basophil count ( 32888494)
  • Basophil percentage of white cells ( 32888494)
  • Mental health study participation (completed survey) ( 31263887)
Interacting Genes 50 interacting genes: ATP2A1 ATP2A2 BCL2L1 CDKL1 CRK CUL4A EDEM1 EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 LAMP1 MPL MPO MTDH NEDD4 NRAS NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PROZ PTPN11 PTPN6 PTPRF PTPRR RAP2A RPTOR SHC1 SLC35B1 SOCS1 SOCS3 SOCS6 SOCS7 SRPK2 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ 59 interacting genes: APP APPL1 AR ARRB1 AXL CBL CD28 CRK CRKL CSF1R DYDC1 EGF EGFR ENKUR EPHA2 ERBB2 ERBB3 ERBB4 FBXL2 FGFR1 FYN GAB1 GHR GOLGA2 GRB2 GRN HCK IGF1R IKZF3 IRS1 IRS2 KIT KRAS KRT15 KRT20 KRT38 LAMB2 LMNA LTBP3 MET MRFAP1L1 PDGFRB PIK3CD RINT1 SEPTIN2 SHC1 SOCS1 SOCS6 SOCS7 SOS1 STAB1 STAT3 SYK TEC TGFBR1 TGFBR2 TRIM23 WASF3 YWHAB
Entrez ID 8660 5296
HPRD ID 02878 04404
Ensembl ID ENSG00000185950 ENSG00000105647
Uniprot IDs Q9P084 Q9Y4H2 O00459
PDB IDs 3FQW 3FQX 2KT1 2XS6 3MTT 3O5Z 6OX7 6U28
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?