CBFA2T3 and CBFA2T2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)
HPRD (in vivo, in vitro)

		CBFA2T3	CBFA2T2
Description		CBFA2/RUNX1 partner transcriptional co-repressor 3	CBFA2/RUNX1 partner transcriptional co-repressor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Nucleolus	Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Response To Hypoxia Transcription, DNA-templated Negative Regulation Of Cell Population Proliferation Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Aerobic Respiration	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Carotid intima media thickness ( 30510157) Carotid intima media thickness (mean) ( 31801372) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hair color ( 26926045) Hemoglobin levels ( 32327693) Immature fraction of reticulocytes ( 32888494) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Social autistic-like traits ( 24133439) Vitiligo ( 27723757)	Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Triglyceride levels ( 32203549)
Interacting Genes		24 interacting genes: ARHGEF6 CBFA2T2 CHRM4 EPM2AIP1 GAS8 GATAD2A GMEB2 HDAC1 HDAC3 MATN2 NUP98 PIN1 PRKAR2A RTN4IP1 RUNX1 RUNX1T1 SEC24A TCF3 VPS37C ZBTB33 ZBTB38 ZBTB4 ZBTB47 ZNF652	34 interacting genes: APP ATN1 ATXN1L BAG4 CBFA2T3 CBFB CEP83 FBXL19 GTF2E1 ID3 KIFC3 KRTAP13-2 LBP MAGEA6 MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 PHAF1 PRDM14 PRDM6 RERE RUNX1 SIKE1 SIN3A SORBS3 TAL2 TCF4 TCP1 ZC2HC1A ZNF652
Entrez ID		863	9139
HPRD ID		04847	04721
Ensembl ID		ENSG00000129993	ENSG00000078699
Uniprot IDs		O75081	O43439
PDB IDs
Enriched GO Terms of Interacting Partners?
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