CBFA2T3 and ZBTB4

Number of citations of the paper that reports this interaction (PubMedID 23251453)
9

Data Source:
BioGRID (two hybrid)

		CBFA2T3	ZBTB4
Description		CBFA2/RUNX1 partner transcriptional co-repressor 3	zinc finger and BTB domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Methyl-CpNpG Binding Protein Kinase Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Response To Hypoxia Transcription, DNA-templated Negative Regulation Of Cell Population Proliferation Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Aerobic Respiration	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Carotid intima media thickness ( 30510157) Carotid intima media thickness (mean) ( 31801372) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hair color ( 26926045) Hemoglobin levels ( 32327693) Immature fraction of reticulocytes ( 32888494) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Social autistic-like traits ( 24133439) Vitiligo ( 27723757)	Appendicular lean mass ( 33097823) Brain morphology (MOSTest) ( 32665545) Corpus callosum posterior volume ( 31530798) Diverticular disease ( 30177863) Height ( 25282103 31562340) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Refractive error ( 32231278) Serum uric acid levels ( 30993211) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		24 interacting genes: ARHGEF6 CBFA2T2 CHRM4 EPM2AIP1 GAS8 GATAD2A GMEB2 HDAC1 HDAC3 MATN2 NUP98 PIN1 PRKAR2A RTN4IP1 RUNX1 RUNX1T1 SEC24A TCF3 VPS37C ZBTB33 ZBTB38 ZBTB4 ZBTB47 ZNF652	17 interacting genes: ANXA2 BANP CALCOCO2 CBFA2T3 CCDC57 CEP70 CEP76 CYSRT1 GOLGA2 HIPK2 HOMER3 KLHL12 PDE4DIP PIBF1 POU6F2 TP53BP2 TRIM23
Entrez ID		863	57659
HPRD ID		04847	11693
Ensembl ID		ENSG00000129993	ENSG00000174282
Uniprot IDs		O75081	B3KVD4 Q9P1Z0
PDB IDs
Enriched GO Terms of Interacting Partners?
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