BHLHE40 and NUMBL

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

BHLHE40

NUMBL

Description basic helix-loop-helix family member e40 NUMB like endocytic adaptor protein
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive function in longevity ( 33607172)
  • Medication use (thyroid preparations) ( 31015401)
  • Multiple sclerosis ( 31604244)
  • Psoriasis vulgaris ( 26626624)
  • Serum alkaline phosphatase levels ( 33547301)
  • Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941)
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941)
  • Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941)
  • Carotid intima media thickness (mean) ( 31801372)
  • Kawasaki disease ( 22446962)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
Interacting Genes 91 interacting genes: AAMP AANAT APH1A ARNTL ATXN1 BHLHE41 BRD7 BYSL CALML3 CCNK CDPF1 CHD3 COX5B CREM DAB1 DAZAP2 DVL3 EHHADH ENO1 FAM83A FBLN1 FXR1 GMCL2 GPSM1 HDAC1 HIVEP1 HNRNPLL KLHDC7B KRTAP1-3 KRTAP19-1 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LARP4 LASP1 LMO3 MAGED1 MCRS1 MYOD1 NAA50 NEK6 NOC4L NUMBL OXNAD1 PDE6G PFDN5 PHF1 PLEKHB2 POU6F2 PRKAA1 PRR20A PRR20B PRR20C PRR20D PRR20E RAD54L2 RBFOX1 RBM23 RBPMS RBPMS2 RHOBTB3 RHOJ ROR2 SETDB1 SIN3A SMAP2 SMARCB1 SMYD1 SOGA1 SOX15 STAT3 STK19 TCF3 TENT5A TENT5B TLE5 TOB2 TOLLIP TTC23 TXNL4B UBE2I USP54 VAC14 VENTX VIM WT1 ZFHX3 ZHX1 24 interacting genes: ACTN1 APP ATXN1 BHLHE40 EGFR EPS15 ESRP2 GAA GPATCH8 GRIP1 MAGED1 NOTCH1 PSMA3 RBFOX1 RIPK1 SIAH1 SPSB3 TAB2 THPO TMC5 TRAF5 TRAF6 UBE3A YWHAG
Entrez ID 8553 9253
HPRD ID 16050 04931
Ensembl ID ENSG00000134107 ENSG00000105245
Uniprot IDs O14503 Q6IB83 A0A0C4DGH3 A8K033 B7Z5W0 Q9Y6R0
PDB IDs 3F0W
Enriched GO Terms of Interacting Partners?
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