NUMBL and RBFOX1

  • Number of citations of the paper that reports this interaction (PubMedID 16713569)
  • 337
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (two hybrid)

NUMBL

RBFOX1

Description NUMB like endocytic adaptor protein RNA binding fox-1 homolog 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941)
  • Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941)
  • Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941)
  • Carotid intima media thickness (mean) ( 31801372)
  • Kawasaki disease ( 22446962)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730)
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Adult body size ( 32376654)
  • Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686)
  • Age at first sexual intercourse ( 34211149)
  • Albumin-globulin ratio ( 29403010)
  • Allergic rhinitis ( 25085501)
  • Alzheimer's disease ( 33074286)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anxiety ( 33859377)
  • Bitter alcoholic beverage consumption ( 31046077)
  • Bitter non-alcoholic beverage consumption ( 31046077)
  • Body mass index ( 28892062 25673413)
  • Brain glucose metabolism (fluorodeoxyglucose uptake) ( 30596066)
  • Brain volume in infants (cerebrospinal fluid) ( 28763065)
  • Cataracts ( 34127677)
  • Cerebellum white matter volume ( 31530798)
  • Chronotype ( 30696823)
  • Cocaine dependence ( 31212010)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Depression ( 33859377 29700475)
  • Evening vs. morning chronotype (sMEQ score) ( 32579418)
  • Extraversion ( 27918536)
  • Feeling worry ( 29500382)
  • General cognitive ability ( 29844566)
  • General risk tolerance (MTAG) ( 30643258)
  • Glaucoma ( 25027321)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • High myopia ( 31816047)
  • Hydrolysed wheat protein allergy ( 31301374)
  • Hyperopia ( 25233373)
  • Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597)
  • Insomnia symptoms (never/rarely vs. usually) ( 30804566)
  • Intelligence (MTAG) ( 29326435)
  • Intracranial aneurysm ( 29531279)
  • joint destruction in rheumatoid arthritis (rapid vs slow) ( 33585033)
  • Major depressive disorder ( 27479909 29728651)
  • Mental health study participation (completed survey) ( 31263887)
  • Metabolite levels ( 31628463)
  • Myopia ( 27182965 25233373)
  • Neurociticism ( 29500382)
  • Neurofibrillary tangles ( 31497858)
  • Neuroticism ( 29255261)
  • Nickel levels ( 26025379)
  • Nontraumatic osteonecrosis of the femoral head ( 32701715)
  • Obesity (extreme) ( 31852448)
  • Obesity-related traits ( 23251661)
  • Optic disc size ( 31809533)
  • Photic sneeze reflex ( 27182965)
  • Pit-and-Fissure caries ( 24556642)
  • Refractive astigmatism ( 30306274)
  • Refractive error ( 23396134 32231278 23474815)
  • Renal cell carcinoma ( 31231134)
  • Rheumatoid arthritis ( 30423114)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Systemising ( 31508503)
  • Systolic blood pressure ( 30224653)
  • Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483)
  • Triglyceride levels ( 34074324)
  • Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926)
  • Type 2 diabetes ( 30130595)
  • Worry too long after an embarrassing experience ( 29500382)
Interacting Genes 24 interacting genes: ACTN1 APP ATXN1 BHLHE40 EGFR EPS15 ESRP2 GAA GPATCH8 GRIP1 MAGED1 NOTCH1 PSMA3 RBFOX1 RIPK1 SIAH1 SPSB3 TAB2 THPO TMC5 TRAF5 TRAF6 UBE3A YWHAG 53 interacting genes: AGR2 AHCY ALG13 ARID5A ATN1 ATXN1 ATXN1L ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HCFC1R1 HNRNPF HSFX1 HSFY1 HYPK KIFAP3 LASP1 LZTS2 MAGED1 MAOB MPG NOC2L NUMBL P4HA3 PCBP4 POGZ PRR20A PRRC2A PSMF1 QKI RBFOX2 RBFOX3 RBM24 RBM47 RBPMS RBPMS2 RHOXF2 SIRPB1 SNRPN STRBP TEX37 TNIP1 TOLLIP UBL3 VENTX
Entrez ID 9253 54715
HPRD ID 04931 16091
Ensembl ID ENSG00000105245 ENSG00000078328
Uniprot IDs A0A0C4DGH3 A8K033 B7Z5W0 Q9Y6R0 A0A6Q8PH77 B7Z1U7 Q59HD3 Q9NWB1 X5D7T5 X5DNY3 X5DP44
PDB IDs 3F0W 2ERR 2N82 4ZKA
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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