MYO5B and RAB11FIP2

Number of citations of the paper that reports this interaction (PubMedID 11495908)
127

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		MYO5B	RAB11FIP2
Description		myosin VB	RAB11 family interacting protein 2
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GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Myosin Complex Cytoplasmic Vesicle Membrane Vesicle Protein-containing Complex Apical Cortex Recycling Endosome Extracellular Exosome	Phagocytic Cup Nucleoplasm Endosome Cytoplasmic Vesicle Membrane Cell Projection Intracellular Membrane-bounded Organelle Recycling Endosome Membrane
	Molecular Function	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Small GTPase Binding Actin Filament Binding	Protein Binding Protein Kinase Binding Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Renal Water Homeostasis Actin Filament Organization Protein Transport Vesicle-mediated Transport Endosomal Transport Vesicle Transport Along Actin Filament	Phagocytosis Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins	Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549 29084231) HDL cholesterol levels ( 32203549) Large HDL particle concentration ( 29084231) Mean diameter of HDL particles ( 29084231) Medium HDL particle concentration ( 29084231) Multiple sclerosis ( 31604244) Myopia ( 27182965) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231) Refractive error ( 32231278) Resistant hypertension ( 31545351) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Total cholesterol levels in HDL ( 29084231)	Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		23 interacting genes: AMOTL2 BNIP2 COIL CXCR2 EFHC2 FAM214B FXR1 GMCL1 KIAA1549 MEI4 MEOX2 POLR1C RAB11A RAB11B RAB11FIP2 RAB25 SHANK3 SMAD3 SMARCA2 TCF4 TRIM3 TRIM54 ZNHIT1	22 interacting genes: AP2A1 CXCR2 EHD1 FAM90A1 FBXO17 FKBP6 HSF2BP ITSN1 KANK2 LRRK2 MARK2 MYO5B OGT PDZD11 PIBF1 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAE YWHAG
Entrez ID		4645	22841
HPRD ID		07582	10548
Ensembl ID		ENSG00000167306	ENSG00000107560
Uniprot IDs		Q7Z7A5 Q9ULV0	Q7L804
PDB IDs		4J5M 4LNZ 4LWZ 4LX0	2GZD 2GZH 2K6S 3TSO 4C4P 6S8X
Enriched GO Terms of Interacting Partners?
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