COPS3 and MCPH1

  • Number of citations of the paper that reports this interaction (PubMedID 29150431)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

COPS3

MCPH1

Description COP9 signalosome subunit 3 microcephalin 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Mean corpuscular volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Neutrophil percentage of white cells ( 32888494)
  • Reticulocyte count ( 32888494)
  • Alcoholic chronic pancreatitis ( 28754779)
  • Birth weight ( 31043758)
  • Carotid intima media thickness ( 30510157)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cytomegalovirus antibody response ( 21993531)
  • Diastolic blood pressure ( 30224653)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Epirubicin-induced leukopenia ( 21799462)
  • Estimated glomerular filtration rate ( 31152163)
  • Gut microbiota relative abundance (Faecalibacterium) ( 33208821)
  • Heel bone mineral density ( 30598549)
  • Intraocular pressure ( 29785010)
  • Metabolite levels ( 23823483)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 24 weeks) ( 28437668)
Interacting Genes 32 interacting genes: ARAF ARF4 C17orf75 CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CSNK2A1 CSNK2B CUL5 FLAD1 FRS3 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 KRT80 LRP2BP MCPH1 MLF1 NABP1 PRXL2B RAF1 SOS1 TP53 68 interacting genes: ABCC2 ACTG1 AKIP1 AKR7A2 ATM ATR B3GALT6 CCDC77 CCT5 CHEK1 COL1A1 COL27A1 COPB2 COPS3 CTSL DNAJA3 DNAJC19 EIF3F EIF4A2 EMG1 ENO1 FBLN1 FLNA GABARAPL2 HNRNPA2B1 HSPD1 KAT5 KDM1A LAMTOR5 LGALS3 MCM2 MCM5 MITD1 MRPL46 MT2A NCCRP1 NMI NR2F1 OBSL1 PHF11 PMVK POLD1 POLR2G PPA1 PPRC1 RACK1 RBM39 RSL24D1 RUVBL2 S100A16 SMARCB1 SMARCC2 SMOX SUPT6H TADA2A TAF1D THAP11 TPT1 TRAP1 TSEN54 UXT VIM WDR53 WDR61 WDR73 WDR75 WNT10B ZMIZ2
Entrez ID 8533 79648
HPRD ID 07262 06174
Ensembl ID ENSG00000141030 ENSG00000147316
Uniprot IDs B4DN01 Q9UNS2 Q8NEM0
PDB IDs 4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N 2WT8 3KTF 3PA6 3SHT 3SHV 3SZM 3T1N 3U3Z 7C5D
Enriched GO Terms of Interacting Partners?
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