SMIM3 and SLC22A1

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

SMIM3

SLC22A1

Description small integral membrane protein 3 solute carrier family 22 member 1
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025)
  • Crohn's disease ( 28067908)
  • Dimensional psychopathology (Arousal) ( 29496196)
  • Inflammatory bowel disease ( 28067908)
  • Apolipoprotein B levels ( 32203549)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Blood protein levels ( 28240269)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Essential hypertension (time to event) ( 32589924)
  • Gout ( 22179738)
  • HOMA-B (corrected for HOMA-IR) ( 30369944)
  • LDL cholesterol levels ( 32203549)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lipoprotein (a) levels ( 26377243)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolic traits ( 21886157)
  • Prostate cancer ( 26034056 21743057)
  • Serum metabolite levels ( 33031748 23093944)
  • Triglyceride levels ( 32203549)
  • Urinary metabolite levels in chronic kidney disease ( 29545352 31959995)
Interacting Genes 52 interacting genes: ASGR2 ATP1B4 ATP6V0C BNIP3 BSCL2 BTNL9 CD53 CD79A CD82 CLDN11 CLDN5 CLDN8 CLEC17A CLEC7A CNIH1 CNIH3 EBP EMP1 EMP3 ERGIC3 FNDC9 GIMAP5 GPR42 IFNGR2 KIR3DL3 LPAR6 LSMEM2 LZTS2 MAL MS4A3 PDCD1LG2 PLP1 PMP22 PNMA1 PSCA RPRM SEC22A SFTPC SGCB SGCZ SLC22A1 SLC38A1 SMCO4 SPACA1 STX1A TEX264 TM4SF18 TMEM182 TMEM218 TMEM31 TRIM14 ZFPL1 30 interacting genes: ALDOA ARID5B CAPN1 CCL2 CD63 CD9 CERS2 CHST12 CLPTM1 CYSTM1 FIS1 FXYD2 GHITM GRM3 KRTCAP2 LAPTM4A LAPTM4B MUC1 OS9 PDZK1IP1 POU2AF1 SERP1 SLC25A11 SMIM24 SMIM3 SPP1 TMBIM4 TMEM147 TMEM179B VAPB
Entrez ID 85027 6580
HPRD ID 12212 04007
Ensembl ID ENSG00000256235 ENSG00000175003
Uniprot IDs Q9BZL3 O15245
PDB IDs
Enriched GO Terms of Interacting Partners?
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