SLC22A1 and CLPTM1

  • Number of citations of the paper that reports this interaction (PubMedID 31318583)
  • 3
  • Data Source:
  • BioGRID (protein complementation assay)

SLC22A1

CLPTM1

Description solute carrier family 22 member 1 CLPTM1 regulator of GABA type A receptor forward trafficking
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein B levels ( 32203549)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Blood protein levels ( 28240269)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Essential hypertension (time to event) ( 32589924)
  • Gout ( 22179738)
  • HOMA-B (corrected for HOMA-IR) ( 30369944)
  • LDL cholesterol levels ( 32203549)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lipoprotein (a) levels ( 26377243)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolic traits ( 21886157)
  • Prostate cancer ( 26034056 21743057)
  • Serum metabolite levels ( 33031748 23093944)
  • Triglyceride levels ( 32203549)
  • Urinary metabolite levels in chronic kidney disease ( 29545352 31959995)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Apolipoprotein B levels ( 32203549)
  • Basal cell carcinoma ( 31174203)
  • Body mass index ( 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x age interaction ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Keratinocyte cancer (MTAG) ( 31174203)
  • LDL cholesterol levels ( 32203549)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 30 interacting genes: ALDOA ARID5B CAPN1 CCL2 CD63 CD9 CERS2 CHST12 CLPTM1 CYSTM1 FIS1 FXYD2 GHITM GRM3 KRTCAP2 LAPTM4A LAPTM4B MUC1 OS9 PDZK1IP1 POU2AF1 SERP1 SLC25A11 SMIM24 SMIM3 SPP1 TMBIM4 TMEM147 TMEM179B VAPB 8 interacting genes: CCR2 CCR4 F2RL1 FZD7 LINC00839 SLC22A1 SLC22A2 UNC93B1
Entrez ID 6580 1209
HPRD ID 04007 07544
Ensembl ID ENSG00000175003 ENSG00000104853
Uniprot IDs O15245 A0A0S2Z3H2 O96005
PDB IDs
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
Tagcloud (Intersection) ?