PPP1R16A and TXNRD1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PPP1R16A	TXNRD1
Description		protein phosphatase 1 regulatory subunit 16A	thioredoxin reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Fibrillar Center Nucleoplasm Cytoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity	Thioredoxin-disulfide Reductase Activity Protein Binding Flavin Adenine Dinucleotide Binding Glutathione Oxidoreductase Activity
	Biological Process	Regulation Of Protein Dephosphorylation Regulation Of Catalytic Activity	Mesoderm Formation Signal Transduction Cell Population Proliferation Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways			PPARA activates gene expression Metabolism of ingested H2SeO4 and H2SeO3 into H2Se Detoxification of Reactive Oxygen Species Interconversion of nucleotide di- and triphosphates Metabolism of ingested MeSeO2H into MeSeH Uptake and function of diphtheria toxin TP53 Regulates Metabolic Genes
Drugs			Arsenic trioxide NADPH Flavin adenine dinucleotide Spermidine Fotemustine Motexafin gadolinium PX-12
Diseases
GWAS		Age at first birth ( 27798627) Blood metabolite levels ( 26401656) Educational attainment ( 25201988) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 32888494 27863252)	Blood protein levels ( 30072576) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Logical memory (delayed recall) in normal cognition ( 29274321) Toenail selenium levels ( 25343990)
Interacting Genes		52 interacting genes: ANTKMT ATP23 ATXN7L2 AVPI1 BATF2 C1orf216 C3orf36 CCDC116 CDCA7L CDH24 CKMT1A CKMT1B DDX27 FSD1 HDAC7 HGS HLA-E IDO1 IL16 KAT5 KRTAP19-5 LY6H LZTS2 MCCD1 MRPL12 MYOM1 NDUFAB1 NEK6 NUTF2 PAPSS1 PBDC1 PHPT1 PPP1CA PPP1CB PPP1CC PRKAB2 PRPF31 PUF60 RFLNB RGMA SCNM1 SUV39H1 TFIP11 TLE5 TPP2 TRIP6 TSSK3 TTC23 TXNRD1 UNKL ZFYVE26 ZNF414	11 interacting genes: DMRTC2 ESR1 ESR2 GLRX2 LINC01554 POU2F1 POU2F2 PPP1R16A THRA TXNDC17 TXNIP
Entrez ID		84988	7296
HPRD ID		16454	03068
Ensembl ID		ENSG00000160972	ENSG00000198431
Uniprot IDs		Q96I34	B7Z2S5 Q16881
PDB IDs			1W1C 2CFY 2J3N 2ZZ0 2ZZB 2ZZC 3QFA 3QFB
Enriched GO Terms of Interacting Partners?
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