PTPN5 and MARCHF5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PTPN5	MARCHF5
Description		protein tyrosine phosphatase non-receptor type 5	membrane associated ring-CH-type finger 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Phosphotyrosine Residue Binding Protein Tyrosine Phosphatase Activity Protein Binding	Protein Binding Zinc Ion Binding GTPase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Protein Polyubiquitination Protein Autoubiquitination Protein Localization To Mitochondrion Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Fission Negative Regulation Of Cell Aging
Pathways		Interleukin-37 signaling
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Myopia ( 27182965) Refractive error ( 32231278)
Interacting Genes		22 interacting genes: CCNQ CLEC4G CUL5 CXCL9 CYB561D2 ENTPD3 FCER1G FYN MAPK1 MAPK3 MARCHF5 MOB1A PLS3 PRKN SAAL1 SLC35B1 SNX4 TERF1 TMEM201 TMEM51 VTI1B ZBTB5	39 interacting genes: AKTIP ANKS6 AQP6 BIK BNIP1 CGRRF1 CREB3 ERGIC3 FATE1 FIS1 FUNDC1 GPX8 HSD17B13 MANBAL MAP1B MFN2 ODF4 PTPN5 RTN4IP1 SAR1A SCD SGPL1 SOD1 STMN4 TANK TIMMDC1 TMEM139 TMEM14B UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2I UBE2N UBE2T UBE2W UTRN YIF1A
Entrez ID		84867	54708
HPRD ID		01472	07909
Ensembl ID		ENSG00000110786	ENSG00000198060
Uniprot IDs		B7Z2F8 P54829 Q86TL3	Q9NX47
PDB IDs		2BIJ 2BV5 2CJZ 5OVR 5OVX 5OW1 6H8R
Enriched GO Terms of Interacting Partners?
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