MARCHF5 and PTPN5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MARCHF5	PTPN5
Description		membrane associated ring-CH-type finger 5	protein tyrosine phosphatase non-receptor type 5
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Nucleoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Zinc Ion Binding GTPase Binding Ubiquitin Protein Ligase Activity	Phosphotyrosine Residue Binding Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Protein Polyubiquitination Protein Autoubiquitination Protein Localization To Mitochondrion Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Fission Negative Regulation Of Cell Aging	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways			Interleukin-37 signaling
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Myopia ( 27182965) Refractive error ( 32231278)
Interacting Genes		39 interacting genes: AKTIP ANKS6 AQP6 BIK BNIP1 CGRRF1 CREB3 ERGIC3 FATE1 FIS1 FUNDC1 GPX8 HSD17B13 MANBAL MAP1B MFN2 ODF4 PTPN5 RTN4IP1 SAR1A SCD SGPL1 SOD1 STMN4 TANK TIMMDC1 TMEM139 TMEM14B UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2I UBE2N UBE2T UBE2W UTRN YIF1A	22 interacting genes: CCNQ CLEC4G CUL5 CXCL9 CYB561D2 ENTPD3 FCER1G FYN MAPK1 MAPK3 MARCHF5 MOB1A PLS3 PRKN SAAL1 SLC35B1 SNX4 TERF1 TMEM201 TMEM51 VTI1B ZBTB5
Entrez ID		54708	84867
HPRD ID		07909	01472
Ensembl ID		ENSG00000198060	ENSG00000110786
Uniprot IDs		Q9NX47	B7Z2F8 P54829 Q86TL3
PDB IDs			2BIJ 2BV5 2CJZ 5OVR 5OVX 5OW1 6H8R
Enriched GO Terms of Interacting Partners?
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