ZNF496 and JADE2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		ZNF496	JADE2
Description		zinc finger protein 496	jade family PHD finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding	Protein Binding Transferase Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways		Generic Transcription Pathway	HATs acetylate histones
Drugs
Diseases
GWAS		Chromium levels ( 26025379) Platelet distribution width ( 32888494)	Adult body size ( 32376654) Age at first birth ( 34211149 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Smoking cessation ( 33082346) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)
Interacting Genes		24 interacting genes: ARR3 CBX3 JADE2 NR3C1 NSD1 PGBD1 POLR3D PPARG RAI1 RNF8 SCAND1 SNIP1 SSX3 SUMO2 SUMO3 SUPT5H TRIM28 ZKSCAN4 ZNF446 ZNF483 ZSCAN12 ZSCAN21 ZSCAN22 ZZZ3	27 interacting genes: C5orf15 CBX8 CDCA7L CSNK2A1 DDX46 FBXO7 FSTL4 GAS2L2 GORASP2 H3-4 ING4 IRAK1 KLK2 MEAF6 PACSIN1 RAPGEF6 SAR1B SASH1 SH2B2 SMAD5-AS1 TCF7 UQCRQ ZBTB3 ZBTB5 ZCCHC10 ZNF417 ZNF496
Entrez ID		84838	23338
HPRD ID		15805	15124
Ensembl ID		ENSG00000162714	ENSG00000043143
Uniprot IDs		Q96IT1	A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1
PDB IDs
Enriched GO Terms of Interacting Partners?
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