ZNF496 and RAI1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		ZNF496	RAI1
Description		zinc finger protein 496	retinoic acid induced 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription, DNA-templated
Pathways		Generic Transcription Pathway	Circadian Clock Heme signaling
Drugs
Diseases
GWAS		Chromium levels ( 26025379) Platelet distribution width ( 32888494)	Body mass index ( 28892062) Body shape index ( 34021172) Caffeine consumption from coffee ( 33287642) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) General cognitive ability ( 29844566) Glycated hemoglobin levels ( 34059833) Hip circumference ( 25673412) Hip index ( 34021172) Low density lipoprotein cholesterol levels ( 32154731) Lymphocyte counts ( 27863252) Monocyte count ( 32888494) Offspring birth weight ( 31043758) Parkinson's disease ( 21738487) Schizophrenia ( 28991256 25056061 29483656) Type 2 diabetes ( 30054458 30297969) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		24 interacting genes: ARR3 CBX3 JADE2 NR3C1 NSD1 PGBD1 POLR3D PPARG RAI1 RNF8 SCAND1 SNIP1 SSX3 SUMO2 SUMO3 SUPT5H TRIM28 ZKSCAN4 ZNF446 ZNF483 ZSCAN12 ZSCAN21 ZSCAN22 ZZZ3	22 interacting genes: CASP2 CCDC144A CDKN1A DDIT3 GADD45A GATA1 GLI1 GRAP GSK3B LZTR1 MAML3 MAPK8IP2 NCOR1 PEMT PIN1 RPS6KA5 TESC TET2 TOPBP1 TTR ULK2 ZNF496
Entrez ID		84838	10743
HPRD ID		15805	07406
Ensembl ID		ENSG00000162714	ENSG00000108557
Uniprot IDs		Q96IT1	Q7Z5J4
PDB IDs
Enriched GO Terms of Interacting Partners?
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