IRS4 and SOCS7

Number of citations of the paper that reports this interaction (PubMedID 12052866)
41

		IRS4	SOCS7
Description		insulin receptor substrate 4	suppressor of cytokine signaling 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Nucleus Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex
	Molecular Function	Insulin Receptor Binding Protein Binding Phosphatidylinositol 3-kinase Binding	Protein Binding SH3 Domain Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Signal Transduction Insulin Receptor Signaling Pathway	Biological_process Negative Regulation Of Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphate Biosynthetic Process
Pathways		IRS-related events triggered by IGF1R
Drugs
Diseases
GWAS			Ovarian cancer ( 23535730)
Interacting Genes		23 interacting genes: CRK CRKL CSNK1G2 EGFR ERBB2 GRB2 IGF1R MAGEL2 MTNR1A MTNR1B NDN NISCH OGT PIK3CA PIK3R1 PRKCZ PTEN PTPN11 PTPN6 RNF41 SOCS6 SOCS7 YWHAG	26 interacting genes: CYSRT1 DAB1 EGFR EXOSC8 GAS2L2 GRB2 HSPB8 IRS2 IRS4 LENG8 MDFI MISP NCK1 NCK2 NSMF OSTF1 PIK3R1 PIK3R2 PLCG1 SH3RF1 SORBS2 SORBS3 TNS2 TUBA1A TUBB4B YES1
Entrez ID		8471	30837
HPRD ID		04620	12299
Ensembl ID		ENSG00000133124	ENSG00000274211
Uniprot IDs		O14654	O14512
PDB IDs
Enriched GO Terms of Interacting Partners?
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