GTPBP3 and PFKL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		GTPBP3	PFKL
Description		GTP binding protein 3, mitochondrial	phosphofructokinase, liver type
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion	Extracellular Region Cytosol 6-phosphofructokinase Complex Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	GTPase Activity Protein Binding GTP Binding	6-phosphofructokinase Activity Protein Binding ATP Binding AMP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding
	Biological Process	TRNA Wobble Uridine Modification TRNA Methylation	Fructose 6-phosphate Metabolic Process Glycolytic Process Response To Glucose Fructose 1,6-bisphosphate Metabolic Process Negative Regulation Of Insulin Secretion Canonical Glycolysis
Pathways		tRNA modification in the mitochondrion	Neutrophil degranulation Glycolysis
Drugs
Diseases
GWAS		Mitochondrial DNA copy number ( 30704525)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Rheumatoid arthritis ( 21505073)
Interacting Genes		29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774	16 interacting genes: APP ATN1 COPS6 GTPBP3 KRTAP10-7 KRTAP4-12 KRTAP5-9 MYD88 PCNT PFKM PRPF40A SHANK3 SUMO2 TESK1 TNFAIP3 YWHAQ
Entrez ID		84705	5211
HPRD ID		12255	01385
Ensembl ID		ENSG00000130299	ENSG00000141959
Uniprot IDs		B7Z563 Q969Y2	P17858 Q7L2M7
PDB IDs
Enriched GO Terms of Interacting Partners?
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