PFKL and GTPBP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		PFKL	GTPBP3
Description		phosphofructokinase, liver type	GTP binding protein 3, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol 6-phosphofructokinase Complex Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Cytoplasm Mitochondrion
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding AMP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Fructose 6-phosphate Metabolic Process Glycolytic Process Response To Glucose Fructose 1,6-bisphosphate Metabolic Process Negative Regulation Of Insulin Secretion Canonical Glycolysis	TRNA Wobble Uridine Modification TRNA Methylation
Pathways		Neutrophil degranulation Glycolysis	tRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Rheumatoid arthritis ( 21505073)	Mitochondrial DNA copy number ( 30704525)
Interacting Genes		16 interacting genes: APP ATN1 COPS6 GTPBP3 KRTAP10-7 KRTAP4-12 KRTAP5-9 MYD88 PCNT PFKM PRPF40A SHANK3 SUMO2 TESK1 TNFAIP3 YWHAQ	29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774
Entrez ID		5211	84705
HPRD ID		01385	12255
Ensembl ID		ENSG00000141959	ENSG00000130299
Uniprot IDs		P17858 Q7L2M7	B7Z563 Q969Y2
PDB IDs
Enriched GO Terms of Interacting Partners?
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