DPY30 and KMT2C

Number of citations of the paper that reports this interaction (PubMedID 24981860)
22

Data Source:
BioGRID (pull down, affinity chromatography technology)

		DPY30	KMT2C
Description		dpy-30 histone methyltransferase complex regulatory subunit	lysine methyltransferase 2C
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Golgi Apparatus Trans-Golgi Network Histone Methyltransferase Complex MLL3/4 Complex Set1C/COMPASS Complex	Nucleus Nucleoplasm Histone Methyltransferase Complex MLL3/4 Complex
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding Acyltransferase Activity Histone Methyltransferase Activity Histone Binding Histone Methyltransferase Activity (H3-K4 Specific) Metal Ion Binding
	Biological Process	Endosomal Transport Histone H3-K4 Methylation	Positive Regulation Of Transcription By RNA Polymerase II Histone H3-K4 Monomethylation
Pathways		PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	PKMTs methylate histone lysines Activation of anterior HOX genes in hindbrain development during early embryogenesis RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 31584380) Male-pattern baldness ( 28196072)
Interacting Genes		33 interacting genes: AK8 AKAP14 ARFGEF1 ASH2L BCAS4 BEND3 CDK17 CFAP91 CHMP2B CREB3L3 DYDC1 DYDC2 FAM136A GPATCH2 GTF2I H3-4 ICA1L KMT2C MRFAP1 OTX1 PRPF3 PRRC2B PSMC3 PSMD14 PXN RSPH3 SETD1A TMCC2 TSPY10 TSPY2 TSPY3 UBC ZFYVE19	11 interacting genes: APPL2 DPY30 H3-4 H3C1 H3C14 H4C1 JUN MAPK14 MTNR1B SMARCB1 TSC22D1
Entrez ID		84661	58508
HPRD ID		17434	06016
Ensembl ID		ENSG00000162961	ENSG00000055609
Uniprot IDs		B4DIS3 Q9C005	Q8NEZ4
PDB IDs		3G36 4RIQ 4RT4 4RTA 6E2H 6PWV	2YSM 2YUK 3UVL 4ERY 5F59 5F6K 6KIW 6MLC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?