COA8 and TRMT61A

		COA8	TRMT61A
Description		cytochrome c oxidase assembly factor 8	tRNA methyltransferase 61A
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Matrix Side Of Mitochondrial Inner Membrane	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex
	Molecular Function		Protein Binding MRNA (adenine-N1-)-methyltransferase Activity
	Biological Process	Response To Reactive Oxygen Species Mitochondrial Cytochrome C Oxidase Assembly Protein Stabilization Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Cytochrome-c Oxidase Activity	TRNA Methylation MRNA Methylation
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Branched-chain amino acid levels (Isoleucine) ( 27898682) Extremely high intelligence ( 29520040) Hemoglobin levels ( 32327693) Intelligence (MTAG) ( 29326435) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494) Schizophrenia ( 25056061)
Interacting Genes		5 interacting genes: AHNAK2 IGHV5-78 INF2 TDRD9 TRMT61A	10 interacting genes: ADSS1 AHNAK2 CLBA1 COA8 IGHV5-78 PLD4 TCL1A TDRD9 TMEM121 TRMT6
Entrez ID		84334	115708
HPRD ID		12637	08810
Ensembl ID		ENSG00000256053	ENSG00000166166
Uniprot IDs		Q96IL0	A0A024R6Q2 Q96FX7
PDB IDs			5CCB 5CCX 5CD1
Enriched GO Terms of Interacting Partners?
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