TRMT61A and COA8

		TRMT61A	COA8
Description		tRNA methyltransferase 61A	cytochrome c oxidase assembly factor 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex	Mitochondrion Matrix Side Of Mitochondrial Inner Membrane
	Molecular Function	Protein Binding MRNA (adenine-N1-)-methyltransferase Activity
	Biological Process	TRNA Methylation MRNA Methylation	Response To Reactive Oxygen Species Mitochondrial Cytochrome C Oxidase Assembly Protein Stabilization Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Cytochrome-c Oxidase Activity
Pathways		tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Branched-chain amino acid levels (Isoleucine) ( 27898682) Extremely high intelligence ( 29520040) Hemoglobin levels ( 32327693) Intelligence (MTAG) ( 29326435) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494) Schizophrenia ( 25056061)	Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
Interacting Genes		10 interacting genes: ADSS1 AHNAK2 CLBA1 COA8 IGHV5-78 PLD4 TCL1A TDRD9 TMEM121 TRMT6	5 interacting genes: AHNAK2 IGHV5-78 INF2 TDRD9 TRMT61A
Entrez ID		115708	84334
HPRD ID		08810	12637
Ensembl ID		ENSG00000166166	ENSG00000256053
Uniprot IDs		A0A024R6Q2 Q96FX7	Q96IL0
PDB IDs		5CCB 5CCX 5CD1
Enriched GO Terms of Interacting Partners?
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