ATRIP and CINP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		ATRIP	CINP
Description		ATR interacting protein	cyclin dependent kinase 2 interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleus
	Molecular Function	Protein Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	Protein Binding
	Biological Process	DNA Damage Checkpoint Signaling DNA Repair	DNA Replication DNA Repair Cell Cycle Cell Division
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Blood protein levels ( 28240269) Body mass index ( 26426971) Refractive error ( 32231278)
Interacting Genes		22 interacting genes: BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAAP100 FAM156A LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA3 SCG2 SPRY2 TASOR2 ZBTB14	42 interacting genes: AMOTL2 APP ATRIP BAALC BLZF1 BTBD2 C1orf109 CCDC112 CCDC33 CFAP161 CLUAP1 COG3 FAM161B FBF1 FNDC11 GAS8 GOLGA2 HNRNPD INCA1 KANK2 MAGEA3 MEOX2 MINAR1 MMADHC MZT1 NDUFB7 PATJ PAX6 POU6F2 PRC1 PRRX1 PSMA1 REL SERTAD1 SNRPD2 SP2 SYCE1 TEPSIN TXNRD3 ZBTB42 ZNF19 ZNF620
Entrez ID		84126	51550
HPRD ID			16715
Ensembl ID		ENSG00000164053	ENSG00000100865
Uniprot IDs		A0A024R2U4 A0A024R307 Q8WXE1	A0A024R6M9 Q9BW66
PDB IDs		4IGK 4NB3 5YZ0
Enriched GO Terms of Interacting Partners?
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