USP9X and PSD4

Number of citations of the paper that reports this interaction (PubMedID 20339350)
27

Data Source:
BioGRID (pull down)

		USP9X	PSD4
Description		ubiquitin specific peptidase 9 X-linked	pleckstrin and Sec7 domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane Growth Cone	Membrane Cleavage Furrow Ruffle Membrane
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Cysteine-type Peptidase Activity Co-SMAD Binding Deubiquitinase Activity Lys48-specific Deubiquitinase Activity	Guanyl-nucleotide Exchange Factor Activity Phospholipid Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Cell Cycle Chromosome Segregation Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Protein Localization Cell Migration Protein Ubiquitination Protein Deubiquitination BMP Signaling Pathway Regulation Of Circadian Rhythm Rhythmic Process Axon Extension Protein Stabilization Cell Division Protein K48-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Demethylation Amyloid Fibril Formation	Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes RHOU GTPase cycle RHOV GTPase cycle Peroxisomal protein import Peroxisomal protein import Amyloid fiber formation
Drugs
Diseases
GWAS		Migraine ( 27322543)	Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Diastolic blood pressure ( 28548082) Estimated glomerular filtration rate ( 31152163 30604766) Glomerular filtration rate ( 29403010) Hematocrit ( 32888494 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Lymphocyte counts ( 32888494) Red blood cell count ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		27 interacting genes: AFDN ALDH1A3 BCL9 CTNNB1 DCX DVL2 ERG FBXW7 GPSM1 MAP3K5 MCL1 NEAT1 PEX5 PSD4 PTEN RICTOR RNF115 RPGR SMAD2 SMAD4 SMN2 SMURF1 STIL SUMO2 TDRD3 UBC VHL	2 interacting genes: LDLRAP1 USP9X
Entrez ID		8239	23550
HPRD ID		02091	15191
Ensembl ID		ENSG00000124486	ENSG00000125637
Uniprot IDs		Q6P468 Q86X58 Q93008	Q8NDX1
PDB IDs		5VBD 5WCH
Enriched GO Terms of Interacting Partners?
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