SETD4 and CHAF1B

		SETD4	CHAF1B
Description		SET domain containing 4	chromatin assembly factor 1 subunit B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex
	Molecular Function	Protein-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H4-K20 Specific) Histone Methyltransferase Activity (H3-K4 Specific)	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding
	Biological Process	Inflammatory Response Peptidyl-lysine Trimethylation Peptidyl-lysine Monomethylation Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Histone H4-K20 Trimethylation Histone H3-K4 Dimethylation Positive Regulation Of Inflammatory Response Regulation Of Cell Proliferation In Bone Marrow Histone H3-K4 Monomethylation	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly
Pathways
Drugs
Diseases
GWAS		Asthma (adult onset) ( 31036433) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497) Obesity-related traits ( 23251661)	Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)
Interacting Genes		3 interacting genes: CHAF1B CIAO2A MORC3	15 interacting genes: APP ASF1A ASF1B CBR1 CDK1 CDK2 CHAF1A H3-4 H3C6 MAL2 PGM1 PRELP RBBP4 SETD4 SUMO2
Entrez ID		54093	8208
HPRD ID		10743	03147
Ensembl ID		ENSG00000185917	ENSG00000159259
Uniprot IDs		A8MTS1 Q9NVD3	Q13112
PDB IDs
Enriched GO Terms of Interacting Partners?
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