CLPP and PLSCR4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLPP	PLSCR4
Description		caseinolytic mitochondrial matrix peptidase proteolytic subunit	phospholipid scramblase 4
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Endopeptidase Clp Complex	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Endopeptidase Activity ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Identical Protein Binding ATPase Binding	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Membrane Protein Proteolysis Proteolysis Involved In Cellular Protein Catabolic Process	Plasma Membrane Phospholipid Scrambling Cellular Response To Lipopolysaccharide
Pathways
Drugs		N-Formylmethionine
Diseases
GWAS			Lymphocyte counts ( 32888494)
Interacting Genes		19 interacting genes: ABI2 C14orf119 CHCHD3 CLPX DTX2 EFEMP1 EFEMP2 GRN KRTAP10-1 NUTF2 P4HA3 PLSCR4 PPP2CA PSMB1 RBPMS STAT4 TNFSF9 TNPO3 TRIM54	62 interacting genes: ABHD17A ADAMTSL4 APLN ATP23 C11orf1 CES1 CLPP CRCT1 DAZAP2 DDIT4L EFEMP2 FCHO1 GATA1 HDHD3 HOXA1 INTS11 ITGB4 KLHL38 KPRP KRT82 KRTAP1-5 KRTAP10-8 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LCE1A LCE1C LCE2B LCE5A LPXN MTUS2 NID2 NOTCH2NLA OXER1 PCSK5 PLSCR1 RAMAC RBP3 RBPMS RPS27A SLC15A2 SSC4D TEKT5 TENM4 TRIM42 TRIP13 TSPAN4 UBA52 UBB UBC YPEL3 ZNF34
Entrez ID		8192	57088
HPRD ID		03074	07401
Ensembl ID		ENSG00000125656	ENSG00000114698
Uniprot IDs		Q16740	E9PHR9 Q9NRQ2
PDB IDs		1TG6 6BBA 6DL7 6H23	3Q5U
Enriched GO Terms of Interacting Partners?
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