FIP1L1 and MIRLET7B

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		FIP1L1	MIRLET7B
Description		factor interacting with PAPOLA and CPSF1	microRNA let-7b
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex	Extracellular Space Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding Protein Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	MRNA Polyadenylation Pre-mRNA Cleavage Required For Polyadenylation	Negative Regulation Of Autophagy Cellular Response To Reactive Oxygen Species Gene Silencing By MiRNA Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Angiogenesis Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) DNA methylation (variation) ( 23725790) Lymphocyte counts ( 32888494) Red blood cell count ( 28453575) Serum VEGFR2 concentration ( 25411163) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		30 interacting genes: APP CPSF4 CSNK2A1 GOLGA2 HMGB1 LIG4 MIR128-2 MIR15B MIR16-2 MIR19A MIR19B1 MIR205 MIR221 MIR34A MIR34B MIR9-3 MIR92A1 MIR92A2 MIRLET7B MIRLET7G MIRLET7I NAA10 OGT PAPOLA PRMT2 PRMT6 SGTA SRPK2 WWOX ZMYND19	99 interacting genes: ADARB1 AGO2 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CELF1 CPSF1 CPSF6 CPSF7 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 ELAVL1 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 P3H1 PDCD11 PGAM5 PLOD1 PTBP1 PUF60 PUM2 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RBM4B RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		81608	406884
HPRD ID		09646
Ensembl ID		ENSG00000145216	ENSG00000284520
Uniprot IDs		Q6UN15
PDB IDs		7K95
Enriched GO Terms of Interacting Partners?
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