FIP1L1 and PAPOLA

Number of citations of the paper that reports this interaction (PubMedID 14749727)
105

Data Source:
BioGRID (pull down)

		FIP1L1	PAPOLA
Description		factor interacting with PAPOLA and CPSF1	poly(A) polymerase alpha
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding	Magnesium Ion Binding RNA Binding Polynucleotide Adenylyltransferase Activity Protein Binding ATP Binding Manganese Ion Binding
	Biological Process	MRNA Polyadenylation Pre-mRNA Cleavage Required For Polyadenylation	MRNA Polyadenylation MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing RNA Polyadenylation
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs Signaling by cytosolic PDGFRA and PDGFRB fusion proteins	mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs			Cordycepin Triphosphate 3-sulfino-L-alanine Triphosphoric acid
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) DNA methylation (variation) ( 23725790) Lymphocyte counts ( 32888494) Red blood cell count ( 28453575) Serum VEGFR2 concentration ( 25411163) Subcortical volume (MOSTest) ( 32665545)	Carboplatin disposition in epthelial ovarian cancer ( 29367611) Copper levels ( 26025379) Metabolite levels ( 23823483) Number of stillbirths in continuous marriage ( 30188897) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		30 interacting genes: APP CPSF4 CSNK2A1 GOLGA2 HMGB1 LIG4 MIR128-2 MIR15B MIR16-2 MIR19A MIR19B1 MIR205 MIR221 MIR34A MIR34B MIR9-3 MIR92A1 MIR92A2 MIRLET7B MIRLET7G MIRLET7I NAA10 OGT PAPOLA PRMT2 PRMT6 SGTA SRPK2 WWOX ZMYND19	6 interacting genes: CPSF1 CPSF3 FIP1L1 SMAD2 SNRPA YWHAE
Entrez ID		81608	10914
HPRD ID		09646	10407
Ensembl ID		ENSG00000145216	ENSG00000090060
Uniprot IDs		Q6UN15	A0A024R6J7 A0A024R6M3 A0A0C4DGK1 P51003
PDB IDs		7K95
Enriched GO Terms of Interacting Partners?
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