NECTIN4 and DEFB121

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		NECTIN4	DEFB121
Description		nectin cell adhesion molecule 4	defensin beta 121
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Integral Component Of Membrane Extracellular Exosome	Extracellular Region
	Molecular Function	Virus Receptor Activity Protein Binding Identical Protein Binding	Molecular_function Protein Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Viral Entry Into Host Cell	Defense Response To Bacterium Innate Immune Response
Pathways		Adherens junctions interactions Nectin/Necl trans heterodimerization	Beta defensins Defensins
Drugs		Enfortumab vedotin
Diseases
GWAS			Liver enzyme levels (alkaline phosphatase) ( 33972514) Prudent dietary pattern ( 28644415)
Interacting Genes		6 interacting genes: AFDN DEFB121 NECTIN1 NECTIN2 PICK1 TIGIT	10 interacting genes: CD40 CLEC2D FAM209A GJA8 IL27RA LAYN LRRC25 NECTIN4 SSMEM1 SYNE4
Entrez ID		81607	245934
HPRD ID		17934	16791
Ensembl ID		ENSG00000143217	ENSG00000204548
Uniprot IDs		K4PZ75 Q96NY8	A0A384MDM0 Q5GRF9 Q5J5C9
PDB IDs		4FRW 4GJT 4JJH
Enriched GO Terms of Interacting Partners?
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