GKAP1 and L3MBTL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GKAP1	L3MBTL2
Description		G kinase anchoring protein 1	L3MBTL histone methyl-lysine binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Chromatin Binding Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process	Signal Transduction Positive Regulation Of Insulin Receptor Signaling Pathway	Chromatin Organization Negative Regulation Of Transcription, DNA-templated
Pathways			SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Chronotype ( 30696823) Daytime nap ( 33568662) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Triglyceride levels ( 32154731)	Adventurousness ( 30643258) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Lamb consumption ( 32066663) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		23 interacting genes: AP3B1 C1orf35 DHFR FAM124B FXR2 HDDC3 HGS HSD11B1 KANK2 KAT5 L3MBTL2 MFAP1 NDN PHOSPHO2 PRKG1 RCOR3 SDCBP SH3BP4 SOX18 TLE1 UBQLN1 UBQLN4 ZCCHC10	53 interacting genes: AMOTL2 BEND7 BHLHB9 BIVM CARD9 CCDC106 CCDC33 CEP76 CYB5R3 EFHC2 EIF4ENIF1 FAM217B GAS8 GKAP1 GOLGA2 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAFA5 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 TUBGCP6 XPNPEP3 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829
Entrez ID		80318	83746
HPRD ID		17042	13954
Ensembl ID		ENSG00000165113	ENSG00000100395
Uniprot IDs		Q5VSY0	A0A0S2Z5X6 Q969R5
PDB IDs			2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
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